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Fig. 3 | Biology Direct

Fig. 3

From: Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation

Fig. 3

Silencing DOCK2 mitigates liver inflammation 3d post-BDL. (A) Representative microphotographs of double IF staining of DOCK2 and F4/80 or (B) iNOS and F4/80. Magnification: 400 fold. Scale bar: 50 μm. (C) Levels of M1 macrophage-related pro-inflammatory cytokines (IL-6, TNF-α, and iNOS) in liver tissues. (D) Representative microphotographs of IHC staining of NLRP3 (E) Caspase 1. Magnification: 200 fold. Scale bar: 100 μm

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