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Fig. 5 | Biology Direct

Fig. 5

From: Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation

Fig. 5

DOCK2 activates RAC1 to participate in BDL-induced liver injury and its deficiency suppressed LPS-induced M1 macrophage polarisation. (A and B) Representative microphotographs of double IF staining of DOCK2 and RAC1 in 3d and 2w BDL livers. Magnification: 600 fold. Scale bar: 50 μm. (C and D) Representative microphotographs of IF staining of GTP-RAC1 in 3d and 2w BDL livers. The quantification of mean fluorescence intensity (MFI) is shown in the right panels. Magnification: 400 fold. Scale bar: 50 μm

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