Fig. 8

Schematic representation on activation of S1R to modulate MAM and ameliorate endoplasmic reticulum stress and mitochondrial calcium overload. S1R exerts cardioprotective effects through PERK and IP3R-VDAC1-MCU signaling pathways
Schematic representation on activation of S1R to modulate MAM and ameliorate endoplasmic reticulum stress and mitochondrial calcium overload. S1R exerts cardioprotective effects through PERK and IP3R-VDAC1-MCU signaling pathways