Fig. 4
From: Doxorubicin PK/PD modeling in multiple myeloma: towards in silico trials

Simulated treatments with the model trained on all data (estimated) and on validation data (prediction). Data points are reported with their 95% CI (red bars). Predictions with the validation model and simulations with the full model are plotted together with their 95% CI (solid lines with green areas and dashed lines with gray areas respectively), calculated with a bootstrap approach. Each simulation started from the initial data point of each treatment. Note that, to improve visualization, different scales have been used on the y-axes in the panels