Table 1 PK model parameters estimated in [12]
From: Doxorubicin PK/PD modeling in multiple myeloma: towards in silico trials
Parameter | Value | Unit |
|---|---|---|
\(V_{max}\) | 1.65\(\cdot \) \(10^{4}\) | nM/h |
\(k_{th}\) | 464 | nM |
\(k_{FE}\) | 5.63\(\cdot \) \(10^{-4}\) | 1/h |
\(K_{BF}\) | 1.22 | 1/h |
\(V_E\) | 100 | \(\mu \)L |
\(V_I\) | 0.07 | \(\mu \)L |