Exploring the association between osteoporosis and kidney stones: a clinical to mechanistic translational study based on big data and bioinformatics

Table 1 Mean femoral bone mineral density (BMD) of 20–29-year-old men and women in NHANES 2007–2010, 2013–2014, and 2017–2020

Region of interest	Mean (gm/cm²)	SD (gm/cm²)	BMD cutoff values for
Region of interest	Mean (gm/cm²)	SD (gm/cm²)	Osteopenia	Osteoporosis
Men (n = 766)
FN BMD	0.969	0.144	0.609–0.825	< 0.609
L1 BMD	0.999	0.123	0.692–0.876	< 0.692
L2 BMD	1.073	0.127	0.756–0.946	< 0.756
L3 BMD	1.081	0.129	0.759–0.952	< 0.759
L4 BMD	1.071	0.127	0.754–0.944	< 0.754
Women (n = 674)
FN BMD	0.893	0.137	0.551–0.756	< 0.551
L1 BMD	0.960	0.128	0.640–0.832	< 0.640
L2 BMD	1.064	0.128	0.744–0.936	< 0.744
L3 BMD	1.100	0.127	0.783–0.973	< 0.783
L4 BMD	1.086	0.121	0.784–0.965	< 0.784

For each of the four regions of interest, low bone density was defined as: (1) osteopenia: a BMD value between 1 standard deviation (SD) and 2.5 SD below the mean of men or women age 20–29 years; and (2) osteoporosis: a BMD value > 2.5 SD below the young reference mean

ISSN: 1745-6150