Fig. 8
From: Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma
Characteristics of metabolism profiling in NOZ cells with DNM1L overexpression. a NOZ cell samples with DNM1L overexpression or not were analyzed using non-targeted metabolomics. b PCA and c OPLS-DA methods were used to analyze the features of samples in positive and negative ion models. d Heatmap showed the expression and class of 31 DEMs (p < 0.05 and VIP > 1) that responded to DNM1L overexpression. The bubble diagram showed the p value and VIP value that determined the importance of each metabolite under this class. e The content of glutamic acid in NOZ cells was detected. n = 3 per group. **p < 0.01