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Fig. 3 | Biology Direct

Fig. 3

From: Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-associated neutrophil heterogeneity and establishes a VEGFA+ neutrophil prognostic model

Fig. 3

Intercellular communication and cytokine-mediated transformation between the GBMAN subpopulation and other cells. (A) Enrichment results of immune factors in neutrophil subpopulations. (B) The shell plot illustrates the communication strength of each neutrophil subgroup with other types of cells. (C) The dot plot displays specific ligand-receptor pairs that mediate interactions between each neutrophil subset

(source) and other cell types (target). (D-F) The Sankey diagram shows the Ligand-Receptor-TF-TargetGene relationships for the three cells with the strongest interaction intensity with VEGFA+GBMAN.

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Biology Direct

ISSN: 1745-6150

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