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Fig. 1 | Biology Direct

Fig. 1

From: ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway

Fig. 1

Pan-cancer analysis of HOMER family gene expression and prognostic value. (A-C) Differential expression levels of HOMER1, HOMER2, and HOMER3 across various cancer types compared to normal tissues, illustrating the dysregulation of these genes in tumors. Statistical analysis was performed using Wilcoxon rank-sum test, with P < 0.05 considered significant. (D-I) Correlation of HOMER family gene expression with overall survival (OS) and disease-specific survival (DSS) in different cancers. Specifically, (D) HOMER1 in bladder cancer (BLCA), lower-grade glioma (LGG), liver cancer (LIHC), and mesothelioma (MESO); (E) HOMER2 in BLCA and lung adenocarcinoma (LUAD); (F) HOMER3 in adrenocortical carcinoma (ACC), LGG, LIHC, MESO, and sarcoma (SARC). (G) HOMER1 associated with DSS in BLCA and lung squamous cell carcinoma (LUSC); (H) HOMER2 in uterine corpus endometrial carcinoma (UCEC) and uveal melanoma (UVM); and (I) HOMER3 in ACC, colon adenocarcinoma (COAD), LGG, LIHC, MESO, rectum adenocarcinoma (READ), and SARC

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Biology Direct

ISSN: 1745-6150

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